With the COVID situation rising across the world since the past one year, several developments have taken place in the field of medical sciences to deal with this pandemic. According to the medical professionals, since the Severe Acute Respiratory Syndrome Coronavirus 2 replication leads to many of the clinical manifestations of COVID-19, therefore, therapies using Antiviral drugs are being investigated for the treatment of COVID-19 in Hyderabad. It is said that these drugs inhibit viral entry.
The viral replication may be particularly active early in the course of COVID-19 and antiviral drugs for COVID 19 may have the greatest impact before the illness progresses to a critical state. Therefore, it is necessary to understand the role of antiviral medications in treating mild, moderate, severe, and critical illness in order to optimize treatment for people with COVID-19.
What is the Drug Cocktail for COVID?
One of the renowned Hospitals in association with Cipla recently launched anti-body cocktail Casirivimab and Imdevimab combination for COVID treatment. The drug is known to have been administered on out-patient basis and the patients tolerated the drug well without incident.
The antibody cocktail drug has also been approved by Drugs Controller General of India. It was observed in Phase 3 trials that the drug significantly reduced the risk of hospitalisation or death by 70% and reduced the duration of symptoms by four days.
Here Mentioned are Some of the Antiviral Drugs for the Treatment of COVID-19:-
There have been many discussions going on regarding, is antibiotic therapy recommended for treatment for COVID-19 patients? To find out the answer, let’s read the article further.
- Remdesivir: It is the only FDA approved drug developed for the treatment of COVID-19. The COVID-19 Treatment Guidelines Panel provides recommendations for using antiviral drugs for COVID-19 treatment based on the available data. The treatment decisions ultimately reside with the patient and their health care provider.
- Chloroquine or Hydroxychloroquine With or Without Azithromycin: Both the drugs are antimalarial drugs. These drugs been used in the treatment of malaria as well as autoimmune diseases. And, both of these drugs have been known to show efficacy against viruses such as HIV, and even coronavirus. However, the panel recommends against the use of chloroquine or hydroxychloroquine with or without azithromycin for the treatment of COVID-19 in hospitalized patients.
- Lopinavir/Ritonavir and Other HIV Protease Inhibitors: Lopinavir is an antiviral that was initially shown to have in vitro activity against SARS in 2003. Ritonavir is a medical drug that is added to lopinavir, to enhance the plasma half-life through the inhibition of cytochrome P-450. As of now, the panel recommends against the use of lopinavir/ritonavir and other HIV protease inhibitors for the treatment of COVID-19 in hospitalized patients.
- Ivermectin: There is a dearth of data regarding the panel’s recommendation for or against the use of ivermectin for the treatment of COVID-19. There is a need for well-designed and well-conducted clinical trials to provide more specific, evidence-based guidance regarding the use of ivermectin in the treatment of COVID-19.
Does Dexamethasone Work Against COVID-19?
Dexamethasone is not a type of novel drug. It is a commonly used steroid with powerful anti-inflammatory properties. This drug is currently the talk of the hour due to the recent claims that it can cut mortality in patients with severe forms of COVID-19 by a third.
The effectiveness of some of the antiviral drugs for the treatment of COVID-19 can be made out from the article above. However, at this point of time, it is important for everyone to get vaccinated against the disease. The choice of opting for Covaxin vs Covishield depends upon you. Both are considered to be quite effective against the coronavirus.
To know more about the vaccines or antiviral drugs for COVID-19, you may get in touch with the suitable medical professionals.